Lake Mburo National Park is a very special place; every part of it is alive with variety, interest and colour. It contains an extensive area of wetland and also harbours several species of mammals and birds found nowhere else in Uganda. Its sculptured landscape, with rolling hills and idyllic lake shores has a varied mosaic of habitats; forest galleries, seasonal and permanent swamps, rich acacia-woodland and grassy valleys which all support a wealth of wildlife.

Lake Mburo is the only park in Uganda with eland, impala and klipspringer. It is also home to the largest population of zebra in Uganda estimated at about 5,000 and probably contains the highest concentration of leopard found anywhere in Uganda. Buffalo, waterbuck, topi and warthog are also very common. Reedbuck and oribi can also be spotted in the open valleys. Hyena, genet, bush pigs and white tailed mongoose are often seen on night game drives.